Role of Epigenetics in Disease

Determined through Analysis of Machinery Disruption (EDDA-MD study)

Björnsson laboratory is focused on understanding the role of epigenetics in human disease.  In an effort to do so, we systematically modify cells and mouse models with CRISPR-Cas9 and explore impact on disease phenotypes such as neurological function and growth. We have made major strides developing therapeutic strategies for Kabuki syndrome and have described a novel disorder (Pilarowski-Bjornsson syndrome).

Björnsson laboratory is located at Sturlugata 8 and is affiliated with the University of Iceland, BioMedical Center in Iceland, Landspítali University Hospital and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University.

Our Principal Investigator: Hans Tómas Björnsson MD PhD, professor of translational medicine and pediatrics at the University of Iceland

The Björnsson laboratory website: Björnsson Laboratory